Clinically Proven Fertility Supplement to Improve Sperm Parameters

FH PRO for Men2018-11-28T02:12:18+00:00

Oxidative stress is implicated in the rise of male infertility, as it is a root cause of decreased sperm count and motility and causes damage to sperm DNA. With comprehensive vitamin and mineral support and targeted antioxidant protection, FH PRO for Men is an evidence-based, doctor-formulated dietary supplement designed to promote male fertility and overall reproductive health by decreasing oxidative stress, improving nutritional status, and improving sperm function. For optimal results, men should begin taking FH PRO three to six months before trying to conceive naturally or initiating ART.*

New Study Results – Three months of treatment with FH PRO for Men resulted in a significant reduction in sperm DNA fragmentation and seminal oxidative stress, and significant improvement in sperm count, progressive motility and morphology in infertile men. See below for study details.

Key Benefits:

  • Formulated and recommended by fertility experts
  • Designed to be used in conjunction with ART
  • Provides effective dosages of key fertility-enhancing ingredients, including CoQ10, L-Carnitine, Arginine, Zinc, Selenium, Vitamin E and Lycopene
  • Offers complete multivitamin support

Clinical Study Results Show Benefit of FH PRO for Infertile Men

Study Title:  Is there a role for oral antioxidants in the treatment of infertile men with high sperm DNA fragmentation?

Authors: Mohamed Arafa, Ahmad Majzoub, Ashok Agarwal, Sami Alsaid, Haitham Elbardisi.

In a prospective clinical trial conducted at the Hamad Medical Center in Doha, Qatar, 101 infertile men with abnormal semen analysis were treated with an antioxidant-based fertility supplement (FH PRO for Men, Fairhaven Health, Bellingham, WA) for 3 months (3 tablets twice daily). Semen samples were analyzed before and after treatment according to WHO 5th edition. Oxidation Reduction Potential (ORP) – a marker of oxidative stress – was measured using the MiOXSYS analyzer, while sperm DNA fragmentation was measured using the Halosperm kit (cut-ff: less than or equal to 30%)

RESULTS

All patients (primary fertility: n-71; secondary infertility: n=30; mean duration: 5.9 +/- 4.2 years; mean age: 35.7 +/- 6.6 years) completed the trial. Compared with the pre-treatment results, there was significant increase in sperm count (from 23.1 +/- 2.6 to 30.8+/-2.8, p<0.001), progressive motility (from 4.1 +/- 0.7 to 9.1 +/-1.1, p<0.001) and normal morphology (from 2.85+/- 0.3 to 4.62+/- 0.3, p<0.001). ORP decreased significantly from 12.2+/- 2.2 to 6.8 +/- 1.6 mv/106/mL (p <0.014). SDF test was done in 72 patients of which 41 had elevated SDF before treatment while 31 were normal. In all patients, SDF significantly decreased from 36.3 +/- 2.3% to 29.04 +/- 1.9%. Specifically, SDF decreased significantly in 35 out of 41 patients with high initial value (from 51.7 +/- 2.2 to 33 +/-2.1, p<0.001). Further SDF became normal in 17 out of 41 patients (41.5%) with high SDF, while 18 out of 41 patients (43.9%) showed significant reduction, but were still high.

CONCLUSIONS

Three months treatment with an antioxidant-based fertility supplement (FH PRO for Men) resulted in significant reduction in sperm DNA fragmentation and seminal oxidative stress, and significant improvement in sperm count, progressive motility and morphology.

These results were presented at the Foundation of Reproductive Medicine annual conference in New York in November 2018.

Supporting Research on Antioxidants

“Antioxidants play an important role in protecting semen from ROS and can improve basic sperm parameters in case of idiopathic oligoasthenoteratozoospermia.” Imamovic Kumalic S and Pinter B. Review of clinical trials on effects of oral antioxidants on basic semen and other parameters in idiopathic oligoasthenoteratozoospermia. Biomed Res Int 2014; 2014:426951.

“The exogenous administration of CoQ10 increases both ubiquinone and ubiquinol levels in semen and can be effective in improving sperm kinetic features in patients affected by idiopathic asthenooospermia.” Balercia G, et al. Coenzyme Q10 and male infertility. J Endocrinol Invest 2009 Jul;32(7):626-32.

“Our results suggest that antioxidant treatment improves sperm quality not only in terms of key seminal parameters and basal DNA damage, but also helps to maintain DNA integrity. Prior administration of antioxidants could therefore promote better outcomes following assisted reproductive techniques.” Abad C, et al. Effects of oral antioxidant treatment upon the dynamics of human sperm DNA fragmentation and subpopulations of sperm with highly degraded DNA. Andrologia 2013 Jun:45(3):211-6.

“Treatment of asthenospermic patients with zinc supplementation leads to restored peroxynitrite levels, arginase activity and NO synthase activity to normal values and gives a statistically significant improvement of semen parameters compared with controls.” Hadwan MH, Almashedy LA, Alsalman AR. Study of the effects of oral zinc supplementation on peroxynitrite levels, arginase activity and NO synthase activity in seminal plasma of Iraqi asthenospermic patients. Reprod Biol Endocrinol 2014 Jan 3:12:1

FH-PRO is offered for sale at fh-pro.com, through trusted health care provider’s offices, and in authorized, reputable pharmacies and health food stores across the United States.

Ingredient Description
Vitamin A (as beta-carotene) Antioxidant; nutritional support; improves IVF outcomes when used in conjunction with other antioxidants
Vitamin C (as ascorbic acid) Antioxidant; nutritional support; improves sperm motility and concentration; improves IVF outcomes when used in conjunction with other antioxidants
Vitamin D3 (as cholecalciferol) Nutritional support; essential for the development of sperm cell nucleus; improves semen quality and count and supports testosterone levels; deficiency widespread, especially in northern US regions
Vitamin E (87.5% as d-alpha tocopherol and 12.5% as mixed tocopherols) Antioxidant; nutritional support; improves sperm quality, including concentration, motility and morphology; shown to significantly improve pregnancy rate and live birth rate of men/couples undergoing ART, when used in conjunction with other antioxidants
Vitamin K (50% as K1 and 50% as K2) Essential nutrient, important for heart health and bone health; dietary deficiency is common
B Complex Vitamins Often referred to as a “complex,” the B vitamins work together to support energy production and cell division, which supports sperm production and function; B vitamins should be supplemented together
B9/Folate (as Quatrefolic) Antioxidant; improves spermatogenesis; boosts sperm quality; significant improvement in pregnancy rates
Vitamin B12(as methylcobalamin) Involved in cellular replication; deficiency leads to reduced sperm count and motility;
Iodine (as potassium iodide) Necessary for the production of thyroid hormones; deficiency is becoming increasingly common
Zinc (as zinc citrate) Increases motility and concentration; enhances sperm maturation and testosterone synthesis; antioxidant that counteracts reactive oxygen species; improves sperm quality; significant improvement in pregnancy rate; increases live birth rate, along with vitamins and carnitines; improvement in live birth rate of men/couples undergoing ART, when used in conjunction with other antioxidants
Selenium (as l-selenomethionine) Antioxidant; participates in sperm production and enhances quality; significant improvement in pregnancy rate; improvement in live birth rate of men/couples undergoing ART, when used in conjunction with other antioxidants
Copper (as copper sulfate) Participates as an electron donor in biological reactions
Manganese (as manganese bisglycinate chelate) Essential for enzymes that protect the mitochondria – the energy powerhouse of the cells – from reactive oxygen species
Chromium (as chromium polynicotinate) Helps regulate sugar metabolism by working with insulin
Molybdenum (as molybdenum glycinate chelate) Essential for virtually all life forms, helps convert sulfur into useable form in the body
L-Carnitine Tartrate Vitamin-like compound that helps transport fatty acids into mitochondria where they can be burned for energy; helps sperm cells create energy needed for motility; seems to prevent cell death (apoptosis), although mechanism unclear – could act as an antioxidant; increases semen volume and motility; significant improvement in pregnancy rate; significant increase in live birth rate, when used in conjunction with vitamins and zinc
CoQ10 (ubiquinone) Antioxidant that protects sperm cells; studies show the more CoQ10 available in seminal fluids, the higher sperm count; improvement in live birth rate of men/couples undergoing ART, when used in conjunction with other antioxidants
N-Acetyl L-Cysteine Improvement in live birth rate of men/couples undergoing ART, when used in conjunction with other antioxidants
Grape Seed Extract (standardized to 85% polyphenols) Powerful antioxidant; animal studies show protective effect against reproductive toxicity and rejuvenation effect of other antioxidants
Lycopene Antioxidant; enhances sperm quality, including count and viability; significant improvement in pregnancy rate; increases the likelihood of successful pregnancy through spontaneous and IVF conception
Benfotiamine Lipid-soluble form of thiamine; effective metabolic precursor of active thiamine; helps ensure thiamine levels are sufficient; prevents oxidative stress
L-Arginine HCl Amino acid necessary for sperm production; precursor for nitric oxide, which required for sperm motility and erectile function
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